Biofabrication technician

Biofabrication technician

Are you a technician with experience in the field op biofabrication techniques? Then this is your chance to work in one of the most innovative centers in the Netherlands in the field of Regenerative Medicine & Cell therapy. We are looking for a biofabrication technician with knowledge and experience in biofabrication techniques.

About ICAT uitklapper, klik om te openen

We would like to welcome you to the Innovation Center for Advanced Therapies (ICAT) in Utrecht. With support of the National Growth Fund, the regional infrastructure of the Utrecht Science Park will be expanded with an innovation center that will be part of the Regenerative Medicine Pilot Plant, a RegMed XB infrastructure of 4 leading regenerative medicine clusters in the Netherlands (namely Leiden, Utrecht, Eindhoven and Maastricht). By collaborating with fundamental and translational researchers, GMP experts, analysts and clinicians from different disciplines, new innovative medicines can be translated more quickly into a production process that is suitable for clinical use within ICAT. Moreover, ICAT has the latest biofabrication and cell therapy technology to develop and produce new therapies for clinical applications. Examples of current therapies and concepts are CAR/TCR T cells, stem cells, DCs and biofabricated advanced in vitro models for drug screening and artificial tissues/organs for transplantation. ICAT consists of three (sub) facilities; a GMP simulation facility, a Biofabrication innovation facility and a GMP production facility. You will be working within the Biofabrication innovation facility on several projects in parallel as part of a multiple project teams in close collaboration with the other sub-facilities. The Biofabrication innovation facility focuses on the combining state-of-art technologies with the fundamental strategy of biofabrication, cells and biomaterials are integrated into biologically functional constructs. Such novel constructs resemble the structure and function of human tissues and can serve as implants for tissue restoration or as disease models to screen drugs and reduce animal testing. The three facilities have all infrastructure and state-of-art equipment to develop biofabrication and gene-and cell therapy products for patients in UMC Utrecht and other hospitals in the Netherlands. In addition, ICAT is a unique center where academic and commercial partners meet in the field of innovation and where the next generation of professionals will be trained.  

Job description uitklapper, klik om te openen

As a biofabrication technician, you will be involved in a broad range of tasks: 

• Involved in a variety of advanced bioprinting technologies 
• Aiming for applications of regenerative medicine, e.g. transplantation, in vitro model and drug discovery 
• Working closely with a biofabrication expert as well as other techniciants and experts within the same team to support the entire workflow of biofabrication from pre-printing to post-printing  
• Monitor and maintain the performance of different bioprinters 
• Prepare and optimize bioink composition for reliable and consistent bioprinting 
• Report and review all required process steps in approved batch records  
• Participate in the follow-up of protocol optimizations 
• Generation and review of manufacturing procedures  
• Responsible for training and education of upcoming internship students 

Your profile uitklapper, klik om te openen

We are looking for an enthusiastic, assertive and organized biofabrication technician who can work accurately and independently. You also have: 

• A Master or PhD? In the engineering field, preferably in the direction of advanced manufacturing or biomedical engineering 
• Experience with advanced manufacturing, preferably under GMP or cleanroom environment (not a must) 
• Experience with various microscopy technique of cell imaging 
• Demonstrated affinity with and interest in the pharmaceutical industry 
• Proven proficiency in written and spoken English 
• Proven proficiency in CAD software and G-code 
• Very good communication and cooperation 
• Critical attitude and perseverance 
• Fulltime available